Over
the past decades, Professor Brimble had published over 210
internationally refereed papers. She had contributed at least 20
review articles or book chapters and had held over 13 patents.
Here is the list of her publications.
Internationally Refereed Journals 2009
1.
"A Novel Approach to Monobenzannulated Spiroketals Using Styrene in the Kulinkovich Reaction"
I. Haym and M. A. Brimble, Synlett, 2009, 2315-2319.
2.
"Synthesis of an Arginine Tagged [Cys155-Arg180] Fragment of NY-ESO-1: Elimination of an Undesired By-product using "In House" Resins"
P. W. R. Harris and M. A. Brimble,
Synthesis, 2009, 3460-3466.
3.
"An Efficient Formal Synthesis of the Human Telomerase Inhibitor (±)-gamma-Rubromycin"
D. C. K. Rathwell, S. -H. Yang, K. Y. Tsang and M. A. Brimble,
Angewandte Chemie International Edition, 2009, 7996-8000.
(Selected for front cover and selected as a very important paper (VIP) -only 5% of papers selected as VIP papers)
4.
"Pyranonaphthoquinone
Derivatives of Eleutherin, Ventiloquinone L, Thysanone and Nanaomycin A
Possessing a Diverse Topoisomerase II Inhibition and Cytotoxicity
Spectrum" J. Sperry, I. Loreno-Castrillejo, M. A. Brimble and F. Machin, Bioorganic and Medicinal Chemistry, 2009, 17, 7131-7137.
5.
"Synthesis of Fish Antifreeze Neoglycopeptides Using Microwave-assisted 'Click Chemistry' "
N. Miller, G. M. Williams and M. A. Brimble,
Organic letters, 2009, 11, 2409-2412.
6.
"A One-pot Approach to Neoglycopeptides using Orthogonal Native Chemical Ligation and Click Chemistry"
D. J. Lee, K. Mandal, P. W. R. Harris, M. A. Brimble and S. B. H. Kent, Organic Letters, 2009, 11, 5270-5273.
7.
"Synthesis of (±)-Wine Lactone and Its Analogues by a Diels–Alder Approach"
P. D. O'Connor, U. B. Kim and M. A. Brimble,
European Journal of Organic Chemistry, 2009, 4405-4411.
(Selected for front cover)
8.
"Synthesis and Reactivity of beta-Methoxymethyl Enecarbamates"
P. D. O'Connor, M. G. Marino, S. M. Guéret and M. A. Brimble,
Journal of Organic Chemistry, 2009, 74, 8893-8896.
9.
"A Novel Approach to the CDE Ring System of Pectenotoxin-4 Triggered by VO(acac)2 Induced Epoxy-Acetalization"
S. Carley and M. A. Brimble, Organic Letters, 2009, 11, 563-566.
10.
"Synthetic
Studies Towards the Anti-inflammatory Agent, Oleocanthal using a
Johnson–Claisen (Orthoester) Rearrangement Strategy"
J. T. B. Kueh, P. D. O'Connor, H. Hügel and M. A. Brimble,
Archive for Organic Chemistry (ARKIVOC), 2009, (vii), 58-71.
11.
"Stability of 5(6)-Carboxyfluorescein in Microwave-Assisted Synthesis of Fluorescein-Labelled O-Dimannosylated Peptides"
R. Kowalczyk, P. W. R. Harris, R. P. Dunbar and M. A. Brimble,
Synthesis, 2009, 2210-2222.
12.
"Influence of alpha-Methyl Substitution of Proline-based Organocatalysts on the Asymmetric alpha-Oxidation of Aldehydes"
S. -T. Tong, M. A. Brimble and D. Barker,
Tetrahedron, 2009, 65, 4801-4807.
13.
"Enantioselective Synthesis of the 3C-Protease Inhibitor (–)-Thysanone using a Staunton-Weinreb Annulation Strategy"
J. Sperry, T. Y. Yuen and M. A. Brimble,
Synthesis, 2009, 2561-2569.
14.
"Biomimetic Studies Towards the Cardinalins: Synthesis of (+)-Ventiloquinone L and an Unusual Dimerisation"
J. Sperry, J. J. P. Sejberg, F. M. Stiemke and M. A. Brimble, Organic and Biomolecular Chemistry, 2009, 7, 2599-2603.
15.
"Use
of Click Chemistry for the Synthesis of Tetrazole-Containing Analogues
of the Neuroprotective Agent Glycyl-L-prolyl-L-glutamic Acid (GPE)"
K.-Y. Hung, P. W. R. Harris and M. A. Brimble,
Synlett, 2009, 1233-1236.
16.
"NNZ-2566: A Gly–Pro–Glu Analogue With Neuroprotective Efficacy in a Rat Model of Acute Focal Stroke" M. J. Bickerdike, G. B. Thomas, D. C. Batchelor, E. S. Sirmianne, W. Leong, H. Lin, F. Sieg, J. Wen, M. A. Brimble, P. W. Harris and P. D. Gluckman, Journal of the Neurological Sciences, 2009, 278, 85-90.
17.
"In vitro Metabolism of Norbormide in Rat, Mouse and Guinea Pig Liver Preparations"
S. Ravindran, B. Hopkins, S. Bova, D. Rennison, M. A. Brimble and M. Tingle,
Environmental Toxicology and Pharmacology, 2009, 27, 144-148.
18.
"Synthesis of Spiroacetal-Nucleosides as Privileged Natural Product-like Scaffolds"
K. W. Choi and M. A. Brimble,
Organic and Biomolecular Chemistry, 2009, 7, 1424-1436.
19.
"Synthesis of Enantiopure Bicyclic? alpha,alpha-Disubstituted Spirolactams via Asymmetric Birch Reductive Alkylation"
S. M. Guéret, P. D. O'Connor and M. A. Brimble, Organic Letters, 2009, 11, 963-966.
20.
"A Facile Cross Metathesis-Radical Cyclisation Approach to Monobenzannulated Spiroketals"
Y.-C. Liu, J. Sperry, D. C. K. Rathwell and M. A. Brimble,
Synlett, 2009, 793-797.
21.
"Synthesis of AE and BE Ring Analogues of the Alkaloid Methyllycaconitine"
H. Guthmann, D. Conole, E. Wright, K. Koerber, D. Barker and M. A. Brimble,
European Journal of Organic Chemistry, 2009, 1944-1960.
22.
"Synthesis
of 6,6-Bisbenzannulated Spiroketals Related to the Rubromycins Using a
Double Intramolecular Hetero-Michael Addition (DIHMA)"
P. Choi, D. C. K. Rathwell and M. A. Brimble,
Tetrahedron Letters, 2009, 50, 3245-3248.
(Invited Article for the special edition to mark the 50th Golden Anniversary of Tetrahedron Letters)
Internationally Refereed Journals 2008
1.
"(1R,1´R,3S,3´S)-5,5´,10,10´-Tetramethoxy-1,1´,3,3´-tetramethyl-3,3´, 4,4´-terahydro-1H,1´H-8,8´-bibenzo[g]isochromene" J. J. P. Sejberg, J., Sperry, K. W. Choi, P. D. W. Boyd and M. A. Brimble,
Acta Crystallographica, Section E: Structure Reports Online, 2008, E64, O758.
2.
"Synthesis of Spiroacetal-Triazoles as Privileged Natural Product-Like Scaffolds Using 'Click Chemistry'" K. W. Choi and M. A. Brimble, Organic and Biomolecular Chemistry, 2008, 6, 3518-3526.
(Selected for front cover and invited paper for special issue to honour Professor Andrew Holmes's 65th birthday)
3.
"A Facile Synthesis of a Spironitrone and a Study of its Cycloaddition and Nucleophilic Addition Reactions" D. Crimmins, I. Dimitrov, P. D. O'Connor, V. Caprio and M. A. Brimble, Synthesis, 2008, 3319-3325.
"The Synthesis of Phosphopeptides Using Microwave-assisted Solid Phase Peptide Synthesis" P. W. R. Harris, G. M. Williams, P. Shepherd and M. A. Brimble, International Journal of Peptide Research and Therapeutics, 2008, 14, 387-392.
7.
"racemic-1-{8´-(tert-Butyldiphenylsilyloxymethyl)-1´,7´-dioxaspiro[5.5] undecan-2´-yl}uridine" K. W. Choi, M. A. Brimble and T. Groutso, Acta Crystallographica, Section E: Structure Reports Online, 2008, E64, O715.
8.
"Diastereoselective Synthesis of Substituted 4-Piperidones and 4-Piperidols Using a Double Mannich Reaction" Y. Chan, H. Guthmann, M. A. Brimble and D. Barker,
Synlett, 2008, 2601-2604.
9.
"Novel Use of N-Carboalkoxy alpha,beta-Unsaturated Iminium Ions as Dienophiles in Diels-Alder Reactions" P. D. O'Connor, K. Koerber and M. A. Brimble, Synlett, 2008, 1036-1038.
10.
"A Facile Enantioselective Synthesis of the Dimeric Pyranonaphthoquinone Core of the Cardinalins" M. A. Brimble, J. S. Gibson, J. J. P. Sejberg and J. Sperry,
Synlett, 2008, 867-870.
11.
"Enantioselective
Synthesis of the Dimeric Pyranonaphthoquinone Core of the Cardinalins
Using a Late-Stage Homocoupling Strategy" J. Sperry, J. S. Gibson, J. J. P. Sejberg and M. A. Brimble,
Organic and Biomolecular Chemistry, 2008, 6, 4261-4270.
12.
"1H and 13C NMR Spectra for C-6 and C-9 Substituted 3-Azabicyclo[3.3.1]nonanes" K. J. Goodall, M. A. Brimble and D. Barker,
Magnetic Resonance in Chemistry, 2008, 46, 75-79.
13.
"3-Allyl-2-hydroxy-5,6,8-trimethoxynaphthalene-1,4-dione" D. C. Rathwell, K. Y. Tsang, K. W. Choi, P. D. W. Boyd, and M. A. Brimble, Acta Crystallographica, Section E: Structure Reports Online, 2008, E64, O1929.
14.
"anti-Helicobacter pylori
Activity of Derivatives of the Phthalide-Containing Antibacterial
Agents Spirolaxane Methyl Ether, CJ-12,954, CJ-13,013, CJ-13,102,
CJ-13,104, CJ-13,108 and CJ-13,015" F. J. Radcliff, J. D. Fraser, Z. E. Wilson, A. M. Heapy, J. E. Robinson, C. J. Bryant, C. L. Flowers and M. A. Brimble,
Bioorganic and Medicinal Chemistry,2008, 16, 6179-6185.
15.
"Buchwald-Hartwig Mono-N-arylation of 2,6-Dihaloisonicotinic Acid Derivatives: A Convenient Desymmetrization Method" A. V. Lorimer, P. D. O'Connor and M. A. Brimble,
Synthesis, 2008, 2764-2770.
16.
"An Efficient Enantioselective Synthesis of the 3C Protease Inhibitor (–)-Thysanone" J. Sperry and M. A. Brimble,
Synlett, 2008, 1910-1912.
17.
"(1R,6R)-1-Methyl-8-azaspiro[5.6]dodecan-7-one" S. M. Guéret, K. W. Choi, P. D. O'Connor, P. D. W. Boyd and M. A. Brimble, Acta Crystallographica, Section E: Structure Reports Online, 2008, E64, O1151.
18.
"An Approach to an Enantioselective Synthesis of Crisamicin A via a Novel Double Hauser-Kraus Annulation Strategy" O. Andrey, J. Sperry, U. S. Larsen and M. A. Brimble,
Tetrahedron, 2008, 64, 3912-3927.
19.
"Synthesis of a C8 Oxygenated Pyranonaphthoquinone: A Useful Precursor to Dimeric Pyranonaphthoquinones" P. Bachu, M. A. Brimble and J. Sperry, Tetrahedron, 2008, 64, 3343-3350.
20.
"Chemoenzymatic
Synthesis of Deoxy Analogues of the DNA Topoisomerase II Inhibitor
Eleutherin and the 3C-Protease Inhibitor Thysanone" P. Bachu, J. Sperry and M. A. Brimble, Tetrahedron, 2008, 64, 4827-4834. (Invited Article for Tetrahedron Symposia-in-Print – "Natural Products Synthesis")
21.
"racemic-Cyclohexane-1,2-diyl Bis(4-nitrobenzoate)" S. T. Tong, D. Barker, K. W. Choi, P. D. W. Boyd and M. A. Brimble, Acta Crystallographica, Section E: Structure Reports Online, 2008, E64, O2174.
22.
"Synthesis of Fluorescein-Labelled O-Mannosylated Peptides as Components for Synthetic Vaccines: Comparison of Two Synthetic Strategies" M. A. Brimble, R. Kowalczyk, P. W. R. Harris, P. R. Dunbar and V. J. Muir, Organic and Biomolecular Chemistry, 20086, 112-121.
23.
"Use of (S)-5-(2-Methylpyrrolidin-2-yl)-1H-tetrazole as a Novel and Enantioselective Organocatalyst for the Aldol Reaction"
S.-T. Tong, P. W. R. Harris, D. Barker and M. A. Brimble, European Journal of Organic Chemistry, 2008, 164-170.
Internationally Refereed Journals 2007
1.
"A Facile Synthesis of Aryl Spirodioxines Based on a 3H,3'H-2,2'-Spirobi(benzo[b][1,4]dioxane) Skeleton" M. A. Brimble, Y.-C. Liu and M. Trzoss,
Synthesis, 2007, 1392-1402.
2.
"Synthesis and Activity Studies of Analogues of the Rat Selective Toxicant Norbormide" D. Rennison, S. Bova, M. Cavalli, F. Ricchelli, A. Zulian, B. Hopkins and M. A. Brimble,
Bioorganic and Medicinal Chemistry, 2007, 15, 2963-2974.
3.
"Synthesis of Thiacrown and Azacrown Ethers Based on a Spiroacetal Framework" M. A. Brimble, M. Nikac and R. Crumbie,
Tetrahedron, 2007, 63, 5220-5226.
4.
"Synthesis of Isotopically Labelled Thiol Volatiles and Cysteine Conjugates for Quantification of Sauvignon Blanc Wine"
K. R. Hebditch, L. Nicolau and M. A. Brimble,
Journal of Labelled Compounds and Radiopharmaceuticals, 2007, 50, 237-243.
5.
"Synthesis of a C-Terminal Thioester Derivative of the Lipopeptide Pam2CSKKKKG Using Fmoc SPPS" P. W. R. Harris, M. A. Brimble, R. Dunbar and S. B. H. Kent,
Synlett, 2007, 713-716.
6.
"A Facile Synthesis of 1,1'-Spirobi(3H,3'H)isobenzofurans"
M. A. Brimble and C. V. Burgess,
Synthesis, 2007, 754-760.
7.
"Synthesis of a Regioisomeric Analogue of the 3C-Protease Inhibitor Thysanone via a Hauser Annulation Strategy" M. A. Brimble, S. I. Houghton and P. D. Woodgate
Tetrahedron, 2007, 63, 880-887.
8.
"Synthesis of the FG Fragment of the Pectenotoxins"
A. M. Heapy, T. W. Wagner and M. A. Brimble, Synlett, 2007, 2359-2362.
9.
"The Influence of Microwave Irradiation on Lipase-Catalyzed Kinetic Resolution of Racemic Secondary Alcohols" P. Bachu, J. S. Gibson, J. Sperry and M. A. Brimble, Tetrahedron Asymmetry, 2007, 18, 1618-1624.
10.
"Synthesis of the anti-Helicobacter pylori Agent (+)-Spirolaxine Methyl Ether and the Unnatural (2"S)-Diastereomer" J. Robinson and M. A. Brimble,
Organic and Biomolecular Chemistry, 2007, 5, 2572-2582.
11.
"Enantioselective Synthesis of an Analogue of Nanaomycin A" M. A. Brimble, P. Bachu and J. Sperry,
Synthesis, 2007, 2887-2893.
12.
"A Short Enantioselective Synthesis of the Topoisomerase II Inhibitor (+)-Eleutherin"
J. S. Gibson, O. Andrey and M. A. Brimble,
Synthesis, 2007, 2611-2613.
13.
"1H and 13C
NMR Spectra of Methylmaleimido- and Methylsuccinimidoanthranilate
Esters of 1-Hydroxymethyl-6-methoxy-3-azabicyclo[3.3.1]nonanes" K. J. Goodall, M. A. Brimble and D. Barker,
Magnetic Resonance in Chemistry, 2007, 45, 695-699.
14.
"Assessing the Molecular Basis for Rat-Selective Induction of the Mitochondrial Permeability Transition by Norbormide" A. Zulian, V. Petronilli, S. Bova, F. Dabbeni-Sala, G. Cargnelli, M. Cavalli, D. Rennison, J. Stäb, O. Laita, D. J. Lee, M. A. Brimble, B. Hopkins, P. Bernardi and F. Ricchelli, Biochimica et Biophysica Acta, Bioenergetics, 2007, 1767, 980-988.
15.
"Synthesis of Aromatic Spiroacetals Related to gamma-Rubromycin Based on a 3H-Spiro[1-benzofuran-2,2'-chromane] Skeleton" K. Y. Tsang and M. A. Brimble,
Tetrahedron, 2007, 63, 6015-6034.
(Invited Paper for Special 50th Anniversary Issue of Tetrahedron)
16.
"Synthesis and Assignment of the Absolute Configuration of the anti-Helicobacter pylori Agents CJ-12,954 and CJ-13,014" M. A. Brimble and C. J. Bryant,
Organic and Biomolecular Chemistry, 2007, 5, 2858-2866.
17.
"Synthesis of Mannosylated Glycopeptides as Components for Synthetic Vaccines"
R. Kowalczyk, M. A. Brimble and R. Dunbar,
Peptide Science, 2007, 88, 539-539. (and in "Advances in Experimental Medicine and Biology," 2009, Vol 611 Peptides for Youth, eds S. Del Valle, E. Escher and R. Dunbar, chapter 155, p 351-352, Springer New York.)
18.
"A Comparative Study of the Different Glycosylation Methods for the Synthesis of D-Mannopyranosides of N-alpha-Fluorenylmethoxycarbonyl-trans-4-hydroxy-L-proline Allyl Ester"
D. J. Lee, R. Kowalczyk, V. J. Muir, P. M. Rendle and M. A. Brimble,
Carbohydrate Research,2007, 342, 2628-2634.
19.
"Peripheral
Administration of a Novel Diketopiperazine, NNZ 2591, Prevents Brain
Injury and Improves Somatosensory-Motor Function Following
Hypoxia-ischemia in Adult Rats" J. Guan, S. Matai, P. W .R. Harris, M. A. Brimble, J.-Y. Wen, R. Zhang and P. D. Gluckman,
Neuropharmacology, 2007, 53, 749-762.
20.
"Synthesis of Indole Analogues of the anti-Helicobacter pylori Compounds CJ-13,015, CJ-13,102, CJ-13,104 and CJ-13,108"
Z. E. Wilson, A. M. Heapy and M. A. Brimble,
Tetrahedron, 2007, 63, 5379-5385.
Internationally Refereed Journals 2006
1.
"Synthesis of the Spiroacetal-Containing anti-Helicobacter pylori Agents CJ-12,954 and CJ-13,014"
M. A. Brimble and C. J. Bryant,
Chemical Communications, 2006, 4506-4508.
2.
"Synthesis of New Aza-C-disaccharides Linking 4-Deoxy-4-amino-beta-L-erythro-furanose to C-2 of D-Glucose and D-Allose"
E. Rodriguez Garcia, M. A. Brimble and P. Vogel,
European Journal of Organic Chemistry, 2006, 3845-3855.
3.
"1H and 13C NMR Data for C-6 Substituted 3-Azabicyclo[3.3.1]nonane-1-carboxylates"
K. Goodall, M. A. Brimble and D. Barker,
Magnetic Resonance in Chemistry, 2006, 44, 980-983.
4.
"Synthesis of Macrocyclic Analogues of the Neuroprotective Agent Glycyl-L-prolyl-L-glutamic Acid (GPE)"
P. W. R. Harris and M. A. Brimble,
Organic and Biomolecular Chemistry, 2006, 4, 2696-2709.
5.
"Synthesis of N-(3-Phenylpropyl)-substituted Tricyclic ABE Ring Analogues of the Alkaloid Methyllycaconitine"
A. Lehmann, C. Brocke, D. Barker and M. A. Brimble,
European Journal of Organic Chemistry, 2006,3205-3215.
6.
"Synthesis
of the Bis-spiroacetal Moiety of the Shellfish Toxins Spirolides B and
D Using an Iterative Oxidative Radical Cyclization Strategy"
K. Meilert and M. A. Brimble,
Organic and Biomolecular Chemistry, 2006, 4, 2184-2192.
(Hot article and selected for front cover page)
7.
"A Novel Bromine-Induced Ring Expansion of the Spiroimine Moiety of the Shellfish Toxin Gymnodimine"
M. A. Brimble, J. E. Robinson, J. Merten, V. Beuzenberg, M. Dragunow, P. Hollandand, D. Mountfort,
Synlett, 2006, 1610-1612.
8.
"Synthesis of Isotopically Labelled Glycyl-L-prolyl-L-glutamic Acid (Glypromate®) and Derivatives" P. W. R. Harris and M. A. Brimble, Journal of Labelled Compounds and Radiopharmaceuticals, 2006,49, 571-581.
9.
"A Facile Synthesis of Fused Aromatic Spiroacetals Based on the 3,4,3',4'-Tetrahydro-2,2'-spirobis(2H-1-benzopyran) Skeleton" M. A. Brimble,C. Flowers, M. Trzoss and K. Y. Tsang, Tetrahedron, 2006, 62, 5883-5896.
10.
"(2''S,5''R,7''S)-2-[2'-(2''-Methyl-1'',6''-dioxaspiro-[4.5]dec-7''-yl)ethylsulfonyl]-1,3-benzothiazole"
G. R. Clark, J. E. Robinson and M. A. Brimble, Acta Crystallographica, Section E: Structure Reports Online, 2006, E62, O1187-O1188.
G. R. Clark, K. Y. Tsang and M. A. Brimble, Acta Crystallographica, Section E: Structure Reports Online, 2006, E62, O1075-O1076.
12.
"Addition of 2-tert-Butyldimethylsilyloxythiophene to Activated Quinones: An Approach to Thia Analogues of Kalafungin"
M. A. Brimble, O. S. Laita and J. E. Robinson,
Tetrahedron, 2006, 62, 3021-3027.
13.
"Synthesis of the ABC Tricyclic Fragment of the Pectenotoxins via Stereocontrolled Cyclization of a gamma-Hydroxyepoxide Appended to the AB Spiroacetal Unit"
R. Halim, M. A. Brimble and J. Merten, Organic and Biomolecular Chemistry,2006, 4, 1387-1399.
Internationally Refereed Journals 2005
1.
"Synthesis of the ABC Fragment of the Pectenotoxins"
R. Halim, M. A. Brimble and J. Merten,
Organic Letters, 2005, 7, 2659-2662.
2.
"The First Enantioselective Total Synthesis of the anti-Helicobacter pylori Agent (+)-Spirolaxine Methyl Ether"
J. Robinson and M. A. Brimble,
Chemical Communications, 2005, 1560-1562.
3.
"Efficient
Synthesis of the Azabicyclo[3.3.1]nonane Ring System in the Alkaloid
Methyllycaconitine Using Bis(alkoxymethyl)alkylamines as
Aminoalkylating Agents in a Double Mannich Reaction"
M. A. Brimble and C. Brocke,
European Journal of Organic Chemistry, 2005, 2385-2396.
4.
"Investigations into the Cellular Actions of the Shellfish Toxin Gymnodimine and Analogues"
M. Dragunow, M. Trzoss, M. A. Brimble, R. Cameron, V. Beuzenberg, P. Holland and D. Mountfort,
Environmental Toxicology and Pharmacology, 2005, 20, 305-312.
5.
"Use of Bis(aminol) Ethers derived from N-(S)-(–)-alpha-Methylbenzylamine in Reactions With Resorcinarenes and Double Mannich Reactions"
B. R. Buckley, P. C. Bulman Page, H. Heaney, E. P Sampler, S. Carley, C. Brocke and M. A. Brimble,
Tetrahedron, 2005, 61, 5876-5888.
6.
"Methyllycaconitine Analogues have Mixed Antagonist Effects at Nicotinic Acetylcholine Receptors"
D. Barker, D. H.-S. Lin, J. E. Carland, C. P.-Y Chu, M. Chebib, M. A. Brimble, G. P. Savage, M. D. McLeod, Bioorganic and Medicinal Chemistry, 2005, 13, 4565-4575.
"Synthesis of Spirolactams via Diels-Alder Addition of 1,3-Butadienes to alpha-Methylenelactams"
D. Crimmins, M. Trzoss and M. A. Brimble,
Archive for Organic Chemistry (ARKIVOC), 2005, (i), 39-52.
15.
"Synthesis
and Pharmacological Evaluation of Side Chain Modified Glutamic Acid
Analogues of the Neuroprotective Agent Glycyl-L-prolyl-L-glutamic Acid
(GPE)"
M. A. Brimble, N. S. Trotter, P. W. R. Harris, M. S. Levi and F. Sieg,
Bioorganic and Medicinal Chemistry, 2005, 13, 519-532.
16.
"Synthesis
and Pharmacological Evaluation of Glycine-Modified Analogues of the
Neuroprotective Agent Glycyl-L-prolyl-L-glutamic Acid (GPE)"
M. Y. H. Lai, M. A. Brimble, D. J. Callis, P. W. R. Harris, M. S. Levi and F. Sieg,
Bioorganic and Medicinal Chemistry, 2005, 13, 533-548.
17.
"Synthesis and Neuroprotective Activity of Analogues of Glycyl-L-prolyl-L-glutamic Acid (GPE) Modified at the alpha-Carboxylic Acid"
N. S. Trotter, M. A. Brimble, P. W. R. Harris, D. J. Callis and F. Sieg,
Bioorganic and Medicinal Chemistry, 2005, 13, 501-517.
Internationally Refereed Journals 2004
1.
"Synthesis and Evaluation of Vasoconstrictor and Vasorelaxant Activity of Norbormide Isomers"
M. A. Brimble, V. J. Muir, B. Hopkins and S. Bova,
Archive for Organic Chemistry (ARKIVOC),2004, (i), 1-11.
2.
"Two Stereoisomers of the Rat Toxicant Norbormide"
P. J. Steel, M. A. Brimble, B. Hopkins and D. Rennison,
"A Double Alkylation – Ring Closing Metathesis Approach to Spiroimines"
M. A. Brimble and M. Trzoss,
Tetrahedron, 2004, 60, 5613-5622.
4.
"Synthesis
of Tricyclic Analogues of Methyllycaconitine Using Ring Closing
Metathesis to Append a B Ring to an AE Azabicyclic Fragment"
D. Barker, M. A. Brimble, M. D. McLeod and G. P. Savage, Organic and Biomolecular Chemistry, 2004, 2, 1659-1669.
5.
"Synthesis of a Novel Nucleoside Based on a Spiroacetal Framework"
M. A. Brimble, J. E. Robinson, K. W. Choi and P. D. Woodgate,
Australian Journal of Chemistry, 2004, 57, 665-668.
6.
"Synthesis of Pyrrolo[3,2-b]benzofurans and Pyrrolo[3,2-b]naphthofurans via Addition of a Silyloxypyrrole to Activated Quinones"
M. A. Brimble, C. Burgess, R. Halim, M. Petersson and J. Ray,
Tetrahedron, 2004, 60, 5751-5758.
7.
"Synthesis of Simple Analogues of Methyllycaconitine – An Efficient Method for the Preparation of the N-Substituted Anthranilate Pharmacophore"
D. Barker, M. A. Brimble and M. D. McLeod,
Tetrahedron, 2004, 60, 5953-5963.
8.
"Application of a Double Mannich Reaction Using Bis(aminol) Ethers in the Synthesis of AE Ring Analogues of Methyllycaconitine"
C. Brocke, M. A. Brimble, D. S. H. Lin and M. D. McLeod,
Synlett, 2004, 2359-2363.
9.
"Synthesis
of the 1,6,8-Trioxadispiro[4.1.5.2]tetradec-11-ene Ring System Present
in the Spirolide Family of Shellfish Toxins and its Conversion to a
1,6,8-Trioxadispiro[4.1.5.2]-tetradec-9-en-12-ol via Base-Induced Rearrangement of an Epoxide"
M. A. Brimble and D. Furkert, Organic and Biomolecular Chemistry, 2004, 2, 3573-3583.
Internationally Refereed Journals 2003
1.
"Addition
of Silyloxydienes to 2,6-Dibromo-1,4-benzoquinone: an Approach to
Highly Oxygenated Bromonaphthoquinones for the Synthesis of Thysanone"
D. Barker, M. A. Brimble, P. Do and P. Turner,
Tetrahedron, 2003, 59, 2441-2449.
2.
"A Convenient Synthesis of 2-(3-Methyl-2,5-dioxopyrrolidin-1-yl)benzoic Acid"
D. Barker, M. A. Brimble and M. D. McLeod,
Synthesis, 2003, 656-658.
3.
"Addition of 2-[(Trimethylsilyloxy)]furan to 2-Acetyl-1,4-benzoquinone Using Chiral Non-racemic Copper(II)-pybox Catalysts"
M. A. Brimble, M. D. K. N. Towers and P. D. Woodgate,
Archive for Organic Chemistry (ARKIVOC), 2003, (i), 43-55.
4.
"C-Glycosylation
of Oxygenated Naphthols with
3-Dimethylamino-2,3,6-trideoxy-L-arabino-hexopyranose and
3-Azido-2,3,6-trideoxy-D-arabino-hexopyranose"
M. A. Brimble, R. M. Davey, M. D. McLeod and M. Murphy,
Australian Journal of Chemistry,2003, 56, 787-794.
5.
"Synthesis of 3-Azido-2,3,6-trideoxy-beta-D-arabino-hexopyranosyl Pyranonaphthoquinone Analogues of Medermycin"
M. A. Brimble, R. M. Davey, M. D. McLeod and M. Murphy,
Organic and Biomolecular Chemistry,2003, 1, 1690-1700.
6.
"Suzuki-Miyaura
Homocoupling of Naphthyl Triflates Using Bis(pinacolato)diboron:
Approaches to the Biaryl Skeleton of Crisamicin A"
M. A. Brimble and M. Y. H. Lai,
Organic and Biomolecular Chemistry, 2003, 1, 2084-2095.
7.
"Synthesis of Proline-Containing Peptides via Ring-Closing Metathesis"
M. A. Brimble, P. W. R. Harris and P. D. Gluckman,
Organic Letters, 2003, 5, 1847-1850.
8.
"Synthesis of the Spiroacetal Fragment of Broussonetine H"
M. A. Brimble, J. H. Park and C. M. Taylor,
Tetrahedron,2003, 59, 5861-5868.
9.
"Synthesis of Spirocyclic Imines: Key Pharmacophores in the Shellfish Toxins Spirolides and Gymnodimine"
M. A. Brimble and M. Trzoss,
Synlett, 2003, 2042-2046.
10.
"Synthesis of Regioisomeric Analogues of Crisamicin A"
M. A. Brimble and M. Y. H. Lai,
Organic and Biomolecular Chemistry, 2003, 1, 4227-4234.
11.
"Use of a Sonogashira-Acetylide Coupling Strategy for the Synthesis of the Aromatic Spiroketal Skeleton of gamma-Rubromycin"
M. A. Brimble, K. Y. Tsang and J. B. Bremner,
Organic Letters, 2003, 5, 4425-4427.
Internationally Refereed Journals 2002
1.
"Uncatalyzed Addition of N-(tert-Butoxycarbonyl)-2-tert-butyldimethylsilyloxypyrrole to Activated Quinones"
M. A. Brimble, R. Halim and M. Petersson,
Tetrahedron Letters, 2002, 43, 4777-4780.
2.
"Synthesis of an Azido Analogue of Medermycin"
M. A. Brimble, R. M. Davey and M. D. McLeod,
Synlett, 2002, 1318-1322. .
3.
"Application of Olefin Metathesis to the Synthesis of ABE Ring Analogues of Methyllycaconitine"
D. Barker, M. D. McLeod, M. A. Brimble and G. P. Savage,
"Synthesis of Aryl Spiroketals Related to the Papulacandins via Allylation of Phthalides"
M. A. Brimble, V. E. Caprio, A. D. Johnston and M. H. Sidford,
Tetrahedron Letters, 2000, 41, 3955-3958.
2.
"Regioselective Asymmetric Aminohydroxylation of Precursors to 2,3,6-Trideoxy-3-aminohexoses"
M. A. Brimble, R. M. Davey and M. D. McLeod,
Tetrahedron Letters, 2000, 41, 5141-5146.
3.
"Diels-Alder Addition of Acyclic Dienes to Chiral Naphthoquinones"
M. A. Brimble, R. J. Elliott and J. F. McEwan,
Australian Journal of Chemistry, 2000, 53, 571-576.
4.
"Enantioselective Synthesis of a Cyclopentannulated Kalafungin Analogue"
M. A. Brimble and J. F. McEwan,
Archive for Organic Chemistry (ARKIVOC), 2000, 1, 909-916.
5.
"Synthesis of an Oxaspirolactone Intermediate for the Synthesis of Spirolides"
M. A. Brimble, F. A. Fares and P. Turner,
Australian Journal of Chemistry, 2000, 53, 845-851.
6.
"Synthesis of a C-Glycosylpyranonaphthoquinone Related to Medermycin"
M. A. Brimble and T. J. Brenstrum,
Tetrahedron Letters, 2000, 41, 2991-2994.
7.
"Reductive Thioalkylation of a Pyranonaphthoquinone"
M. A. Brimble and M. R. Nairn,
Journal of the Chemical Society, Perkin Transactions 1, 2000, 317-322.
8.
"Synthesis of Naphthyl C-Glycosides of Rearranged Tri-O-benzyl-2-deoxy-D-glucose"
M. A. Brimble and T. J. Brenstrum,
Tetrahedron Letters, 2000, 41, 1107-1110.
9.
"A Titanium Naphtholate Approach for the Synthesis of Analogues of Griseusin A"
M. A. Brimble, M. R. Nairn and J. S. O. Park,
Journal of the Chemical Society, Perkin Transactions 1, 2000, 697-709.
10.
"Diels-Alder Cycloaddition of Cyclopentadiene to a Bis-naphthoquinone"
M. A. Brimble and L. J. Duncalf,
Molecules, 2000, 5, 162-166.
Internationally Refereed Journals 1999
1.
"Synthetic Studies towards the B,C,D,E Fragment of Antibiotic CP44,161"
P. A. Allen, M. A. Brimble and H. Prabaharan,
Synlett, 1999, 295-298.
2.
"Synthesis of Analogues of Griseusin A"
M. A. Brimble, M. R. Nairn and J. Park,
Organic Letters, 1999, 1, 1459-1462.
3.
"Deprotonation and Alkylation of 2-Methyl-4,5,6,7-tetrahydrofuro-3H-azepine"
M. A. Brimble and S. Gorsuch,
Australian Journal of Chemistry, 1999, 52, 965-969.
4.
"The Synthesis of Oxygenated Naphthyl Stannanes Possessing ortho-Methoxy Substituents
for use in Stille Coupling Reactions"
M. A. Brimbleand L. J. Duncalf,
Australian Journal of Chemistry, 1999, 52, 19-29.
5.
"Reactions
of Semiquinones in Aqueous Solution. A Comparison of One Electron
Reduction of Kalafungin and Analogues With Other Semiquinones Using
Pulse Radiolysis"
R. F. Anderson, M. A. Brimble, M. R. Nairn and J. E. Packer,
Journal of the Chemical Society, Perkin Transactions 2, 1999, 475-479.
6.
"Addition of a Grignard Reagent to Bis-spiroacetal Aldehydes: Appendage of a Tetrahydrofuran Ring"
M. A. Brimble and H. Prabaharan,
Journal of the Chemical Society, Perkin Transactions 1, 1999, 2795-2802.
7.
"Reaction of Bromonaphthofurans with Bis(pinacolato)diboron"
M. A. Brimble and F. Issa,
Australian Journal of Chemistry, 1999, 52, 1021-1028.
Internationally Refereed Journals 1998
1.
"Asymmetric Michael Addition of 2-Trimethylsilyloxyfuran to Chiral Naphthoquinones"
M. A. Brimble, J. F. McEwan and P. Turner,
Tetrahedron Asymmetry, 1998, 9, 1257-1267.
2.
"Addition of Cyclopentadiene and 2-Trimethylsilyloxyfuran to Quinones Bearing a Menthyl Ester Chiral Auxiliary"
M. A. Brimble, L. J . Duncalf, D. C. W. Reid and T. R. Roberts,
Tetrahedron, 1998, 54, 5363-5374.
3.
"Synthesis of C-2 Functionalised 1,6,8-Trioxadispiro[4.1.5.3]pentadec-13-enes"
M. A. Brimble, P. R. Allen and F. Fares,
Journal of the Chemical Society, Perkin Transactions 1,1998, 2403-2411.
4.
"Reductive Thioalkylation of a Kalafungin Analogue"
M. A. Brimble and M. R. Nairn,
Tetrahedron Letters, 1998, 39, 4879-4882.
5.
"Synthesis of a Dimeric Pyranonaphthoquinone via a Novel Double Furofuran Annulation Strategy"
M. A. Brimble, D. Neville and L. J. Duncalf,
Tetrahedron Letters, 1998, 39, 5647-5650.
6.
"Synthesis of Chiral Diazanedicarboxylates"
M. A. Brimble, M. J. Duckworth and C. Y. K. Lee,
Australian Journal of Chemistry, 1998, 51, 907-913.
7.
"Synthesis of a Novel Cage Compound via Oxidative Rearrangement of a Dihydronaphthofuran"
M. A. Brimble, R. J. R. Elliott and P. Turner,
Tetrahedron, 1998, 54, 14053-14058.
8.
"Synthesis of 7-Methoxy-3',4',5',6'-tetrahydrospiro[isobenzofuran-1(3H), 2'-pyran]-3-one and 5,7-Dimethoxy-3',4',5',6'-tetrahydrospiro[isobenzofuran- 1(3H), 2'-pyran]-3-one"
M. A. Brimble and S. Chan,
Australian Journal of Chemistry, 1998, 51, 235-242.
9.
"Synthesis and Herbicidal Activity of [3R*,5S*,6S*]-3-Benzyloxy-5-methoxy-1,7-dioxaspiro[5.5]undecane and [3R*,5S*,6S*]-3-Methoxy-5-benzyloxy-1,7-dioxaspiro-[5.5]undecane"
M. A. Brimble, R. J. Furneaux and A. D. Johnston,
Journal of Organic Chemistry, 1998, 63, 471-479.
10.
"Synthesis of Crown Ethers Based on a Spiroacetal Framework"
M. A. Brimble and A. D. Johnston,
Journal of the Chemical Society, Perkin Transactions 1,1998, 265-270.
11.
"Addition of Allylsilanes to an Oxy-Stabilized Carbenium Ion on a 1,7-Dioxaspiro[5.5]undecane Ring System"
M. A. Brimble, F. Fares and P. Turner,
Journal of the Chemical Society, Perkin Transactions 1, 1998, 677-684.
12.
"Approaches to the D-E Ring of the Polyether Antibiotic Salinomycin Using Sharpless Asymmetric Dihydroxylation"
M. A. Brimble and H. Prabaharan,
Tetrahedron, 1998, 54, 2113-2128.
13.
"Asymmetric Azo-ene Reactions Using the Chiral Azo-enophile Di-(–)-(1R,2S)-2-phenyl-1-cyclohexyl Diazenedicarboxylate"
M. A. Brimble and C. Y .K. Lee,
Tetrahedron Asymmetry, 1998, 9, 873-884.
14.
"Asymmetric Diels-Alder Addition of Cyclopentadiene to Chiral Naphthoquinones"
M. A. Brimble, J. F. McEwan and P. Turner,
Tetrahedron Asymmetry, 1998, 9, 1239-1255.
15.
"Double Furofuran Annulation to a Bis-naphthoquinone: An Approach to Dimeric Pyranonaphthoquinones"
M. A. Brimble, L. J. Duncalf and D. Neville,
Journal of the Chemical Society, Perkin Transactions 1, 1998, 4165-4173.
Internationally Refereed Journals 1997
1.
"Synthesis of a New Spiroacetal Based Herbicide"
M. A. Brimble, R. J. Furneaux and A. D. Johnston,
Tetrahedron Letters, 1997, 38, 3591-3594.
2.
"Kinetic Resolution in the Asymmetric Dihydroxylation of 1,7-Dioxaspiro[5.5]-undec-4-enes"
M. A. Brimble and A. D. Johnston,
Tetrahedron Asymmetry, 1997, 8, 1661-1676.
3.
"Addition of Silyloxydienes to 2-Substituted 1,4-Benzoquinones and 1,4-Naphthoquinones"
M. A. Brimble and R. J. Elliott,
Tetrahedron, 1997, 53, 7715-7730.
4.
"Use
of Bis(oxazoline)-Metal Complexes as Chiral Catalysts for Asymmetric
Diels-Alder Reactions Using 2-Acetyl-1,4-naphthoquinone as Dienophile"
M. A. Brimble and J. F. McEwan,
Tetrahedron Asymmetry, 1997, 8, 4069-4078.
5.
"Crystal Structures of (3S*,4S*,5S*,6S*)-3,4-Epoxy-1,7-dioxaspiro[5.5]undecan-5-ol, (3R*,5S*,6S*)-1,7-Dioxaspiro[5.5]undec-3,5-diyl Diacetate and (4S*,5S*,6S*)-1,7-Dioxaspiro[5.5]undecan-4,5-diol"
M. A. Brimble, A. D. Johnston, T. W. Hambley and P. Turner,
Australian Journal of Chemistry, 1997, 50, 123-127.
6.
"Facile Bisarylation of Aldehydes Using Titanium Naphtholates"
M. A. Brimble and E. Oppen,
Synthetic Communications, 1997, 27, 989-1007.
7.
"Synthesis of the Monomeric Unit of gamma-Actinorhodin"
M. A. Brimble, L. J. Duncalf and S. J. Phythian,
Journal of the Chemical Society, Perkin Transactions 1, 1997, 1399-1403.
8.
"Synthesis of 8-Bromokalafungin as an Intermediate for the Preparation of C-Glycoside Derivatives"
M. A. Brimble, M. R. Nairn, H. Prabaharan and N. B. Walters,
Australian Journal of Chemistry, 1997, 50, 711-718.
Internationally Refereed Journals 1996
1.
"Synthesis of (E)-1-Bromo-3-ethyl-3-pentene"
M. A. Brimble and M. K. Edmonds,
Synthetic Communications, 1996, 26, 243-251.
2.
"Synthesis of Chiral Hydroxylated Farnesene Derivatives"
M. A. Brimble, J. A. Spicer and D. D. Rowan,
Synthesis, 1996, 116-122.
3.
"Synthesis of Aromatic Spiroacetals"
M. A. Brimble, G. M. Horner and R. J. Stevenson,
Australian Journal of Chemistry, 1996, 49, 189-196.
4.
"Woodward-Prevost Reactions of 1,7-Dioxaspiro[5.5]undec-4-enes"
M. A. Brimble and M. R. Nairn,
Journal of Organic Chemistry,1996, 61, 4801-4805.
5.
"Synthesis of Spiroketals Related to Griseusin A"
M. A. Brimble and M. R. Nairn,
Molecules, 1996, 1, 3-14.
6.
"Synthesis of Tricyclic Aryl Spiroacetals Related to the Papulacandins"
M. A. Brimble and S. G. Robinson,
Tetrahedron, 1996, 52, 9553-9565.
7.
"Synthesis and Ene Reactions of Di-(–)-menthyl Diazenedicarboxylate"
M. A. Brimble, C. H. Heathcock and G. N. Nobin,
Tetrahedron Asymmetry, 1996, 7, 2007-2016.
Internationally Refereed Journals 1995
1.
"Synthesis of an Actinorhodin Monomer"
M. A. Brimble, L. J. Duncalf and S. J. Phythian,
Tetrahedron Lettters, 1995, 36, 9202-9210.
2.
"Enantioselective Synthesis of the Apple Aroma Constituent 1,3,3-Trimethyl-2,7-dioxabicyclo[2.2.1]heptane via Asymmetric Dihydroxylation"
M. A. Brimble, D. D. Rowan and J. A. Spicer,
Synthesis, 1995, 1263-1266.
3.
"Synthesis of Arizonin C1"
M. A. Brimble, S. J. Phythian and H. Prabaharan,
Journal of the Chemical Society, Perkin Transactions 1, 1995, 2855-2860.
4.
"Diastereoselective Addition of 2-Trimethylsilyloxyfuran to (S)-(+)-2-(p-Tolylsulfinyl)-1,4-benzoquinone"
M. A. Brimble, L. J. Duncalf and D. C. W. Reid,
Tetrahedron Asymmetry, 1995, 6, 263-269.
5.
"Identification of Conjugated Triene Oxidation Products of alpha-Farnesene in Appleskin"
J. M. Allen, M. A. Brimble, S. Fielder, D. D. Rowan and J. A. Spicer,
Journal of Agriculture and Food Chemistry, 1995, 43, 2040-2045.
6.
"Synthesis of Bis-2,5-linked Tetrahydrofurans via Iodoetherification"
M. A. Brimble and M. K. Edmonds,
Tetrahedron, 1995, 51, 9995-10012.
Internationally Refereed Journals 1994
1.
"Asymmetric Dihydroxylation of alpha- and beta-Farnesene"
M. A. Brimble, D. D. Rowan and J. A. Spicer,
Tetrahedron Letters, 1994, 35, 9445-9446.
2.
"Formal Synthesis of the Juglomycins "
M. A. Brimble and E. Ireland,
Journal of the Chemical Society, Perkin Transactions 1, 1994, 3109-3104.
3.
"Synthesis of Conjugated Trienes and Related Oxidation Products of alpha-Farnesene"
M. A. Brimble, D. D. Rowan and J. A. Spicer,
Australian Journal of Chemistry,1994, 47, 1979-1988.
4.
"A Short Synthesis of Deoxyfrenolicin"
M. A. Brimble and S. M. Lynds,
Journal of the Chemical Society, Perkin Transactions 1, 1994, 493-496.
5.
"Synthesis of trans- and cis-14-Phenylsulfonyl-1,7,9-trioxadispiro[5.1.5.3]hexadecane"
M. A. Brimble and C. J. Rush,
Journal of the Chemical Society, Perkin Transactions 1, 1994, 497-500.
6.
"Synthesis of Bicyclic Pyrazinones via Addition of Heterocyclic Amines to a Nitro-alkene"
M. A. Brimble and A. D. Johnston,
Tetrahedron,1994, 50, 4887-4896.
7.
"Directed ortho Metallations of Tertiary Benzamides Using Lactones as Electrophiles"
T. J. Brenstrum, M. A. Brimble and R. J. Stevenson,
Tetrahedron, 1994, 50, 4897-4904.
Internationally Refereed Journals 1993
1.
"Dihydroxylation of 1,7-Dioxaspiro[5.5]undec-4-enes"
M. A. Brimble and M. R. Nairn,
Australian Journal of Chemistry, 1993, 46, 195-201.
2.
"Allylic Amination by the Lewis-Acid-Mediated Ene Reaction of Diethyl Azodicarboxylate with Alkenes"
M. A. Brimble and C. H. Heathcock,
Journal of Organic Chemistry, 1993, 58, 5261-5263.
3.
"Synthesis of 5-epi-Arizonin B1 and 5-epi-Arizonin C1"
M. A. Brimble and S. J. Phythian,
Tetrahedron Letters, 1993, 34, 5813-5814.
4.
"Structure of a Bis-spiroacetal, cis-14-Phenylsulphonyl-1,7,9-trioxadispiro[5.1.5.3]hexadecane"
E. N. Baker, M. A. Brimble, G. E. Norris and C. J. Rush,
Australian Journal of Chemistry, 1993, 46, 1929-1939.
Internationally Refereed Journals 1992
1.
"Synthesis of a Pyranonaphthoquinone-Spiroacetal"
M. A. Brimble and M. R. Nairn,
Journal of the Chemical Society, Perkin Transactions 1, 1992, 579-583.
2.
"Synthesis of Deuterated Hexenols"
T. J. Brenstrum, M. A. Brimble, C. J. Rush, J. G. Shaw and D. C. W. Reid,
Journal of Labelled Compounds and Radiopharmaceuticals, 1992, 8, 629-635.
3.
"Allylic Functionalization of the 1,7-Dioxaspiro[5.5]undec-4-ene and 1,6,8-Trioxadispiro[4.1.5.3]pentadec-13-ene Ring Systems"
M. A. Brimble, M. K. Edmonds and G. M. Williams,
Tetrahedron, 1992, 48, 6455-6466.
4.
"Synthesis of the Bis-spiroacetal Moiety of 17-epi-20-Deoxysalinomycin"
M. A. Brimble and G. M. Williams,
Journal of Organic Chemistry, 1992, 57, 5818-5822.
Internationally Refereed Journals 1991
1.
"Approaches to a Key Lactone Intermediate Required for the Synthesis of Pyranonaphthoquinone Antibiotics"
M. A. Brimble and J. A. Spicer,
Australian Journal of Chemistry, 1991, 44, 197-205.
2.
"Synthesis of 5'-Deoxyjuglomycin A and 5'-Methoxyjuglomycin A"
M. A. Brimble, E. Ireland and S. J. Phythian,
Tetrahedron Letters, 1991, 32, 6417-6420.
3.
"Highly Stereoselective syn-Hydroxylation of Spiroketals"
M. A. Brimble, M. R. Nairn and Y. Wu,
Tetrahedron Letter, 1991, 32, 4049-4050.
4.
"Chemistry of Bis-spiroacetals: Synthesis of cis- and trans-1-(2-Methyl-1,6,8-trioxadispiro[4.1.5.3]pentadec-13-en-2-yl)methanol"
M. A. Brimble, G. M. Williams and R. Baker,
Journal of the Chemical Society, Perkin Transactions 1, 1991, 2221-2227.
Internationally Refereed Journals 1990
1.
"Synthesis of the Insect Feeding Deterrent Peramine via Michael Addition of a Pyrrole Anion to a Nitroalkene"
M. A. Brimble and D. D. Rowan,
Journal of the Chemical Society, Perkin Transactions 1, 1990, 311-314.
2.
"Synthesis of the Griseusin A Ring System"
M. A. Brimble and M. R. Nairn,
Journal of the Chemical Society, Perkin Transactions 1, 1990, 169-171.
3.
"Synthesis of 5-epi-7-Deoxykalafungin and 5-epi-7-O-Methylkalafungin"
M. A Brimble and S. J. Stuart,
Journal of the Chemical Society, Perkin Transactions 1, 1990, 881-885.
4.
"Effect of the Fungal Metabolite Peramine and Analogues on Feeding and Development of the Argentine Stem Weevil (Listronotus bonariensis )"
M. A. Brimble, D. D. Rowan and J. J. Dymock,
Journal of Chemical Ecology, 1990, 16, 1683-1695.
5.
"The Chemistry of Bis-spiroacetals. Synthesis of the Novel 1,7,9-Trioxadispiro-[5.1.5.3]hexadecane Ring System"
M. A. Brimble, C. J. Rush, G. M. Williams and E. N. Baker,
Journal of the Chemical Society, Perkin Transactions 1, 1990, 414-416.
6.
"Stereocontrolled Synthesis of a Key Lactone Intermediate Required for the Synthesis of Salinomycin"
M. A. Brimble,
Australian Journal of Chemistry, 1990, 43, 1035-1046.
7.
"Synthesis of a Functionalised Bis-spiroacetal"
M. A. Brimble, G. M. Williams, R. Baker and M. James,
Tetrahedron Letters, 1990, 31, 3043-3046.
8.
"Allylic Oxidation of Unsaturated Spiroketals"
M. A. Brimble, M. K. Edmonds and G. M. Williams,
Tetrahedron Letters, 1990, 31, 7509-7512.
Internationally Refereed Journals 1989
1.
"Synthesis of the cis-3a,8b-Dihydrofuro[3,2-b]benzofuran-2(3H)-one Ring System via a Furofuran Annulation to Activated Benzoquinones"
M. A. Brimble, M. T. Brimble and J. J. Gibson,
Journal of the Chemical Society, Perkin Transactions 1, 1989, 179-184.
Internationally Refereed Journals 1988
1.
"The Chemistry of Bis-spiroacetals. Synthesis of the 1,6,8-Trioxadispiro[4.1.5.3]pentadecane Ring System"
R. Baker and M. A. Brimble,
Journal of the Chemical Society, Perkin Transactions 1, 1988, 125-131.
2.
"A Facile Synthesis of Spiroketals"
M. A. Brimble, D. L. Officer and G. M. Williams,
Tetrahedron Letters, 1988, 29, 3609-3612.
3.
"Synthesis of 2-Methylpyrrolo[1,2-a]pyrazin-1(2H)-one"
M. A. Brimble, M. T. Brimble, R. Hodges and G. A. Lane,
Australian Journal of Chemistry, 1988, 41, 1583-1590.
4.
"Synthesis of Peramine, an Insect Feeding Deterrent Mycotoxin from Acremonium Lolii"
M. A. Brimble and D. D. Rowan,
Journal of the Chemical Society, Chemical Communications, 1988, 978-979.
5.
"Rearrangement of a Furo[3,2-b]naphtho[2,1-d]furan to a Pyranonaphthoquinone"
M. A. Brimble, R. Hodges and S. J. Stuart,
Tetrahedron Letters,1988, 29, 5987-5990.
Internationally Refereed Journals 1987
1.
"1,4-Addition of 2-Trimethylsilyloxyfuran to Quinones: A Facile Route to the Furo[3,2-b]benzofuran Nucleus"
M. A. Brimble, M. T. Brimble, J. J. Gibson, R. Baker, A. A. Kee and M. J. O'Mahon,
Tetrahedron Letters, 1987, 28, 4891-4892.
Internationally Refereed Journals 1986
1.
"Synthesis of Two Key Intermediates Required for the Construction of the Bis-spiroacetal Moiety of epi-17-Deoxy-(O-8)-salinomycin"
R. Baker and M. A. Brimble,
Tetrahedron Letters, 1986, 27, 3311-3314.
Internationally Refereed Journals 1985
1.
"The Chemistry of Spiroacetals. Approaches to the Novel 1,6,8-trioxadispiro[4.1.5.3]pentadecane Ring System"
R. Baker and M. A. Brimble,
Journal of the Chemical Society, Chemical Communications, 1985, 78-80.
2.
"Determination
of the Stereochemistry of
2,2-Dimethyl-1,6,8-trioxadispiro[4.1.5.3]pentadec-13-ene Formed by Two
Sequential Cyclization Reactions Using High Field 1H NMR Spectroscopy"
R. Baker, M. A. Brimble and J. A. Robinson,
Tetrahedron Letters, 1985, 26, 2115-2118.
3.
"Diastereoselective Diels-Alder Reactions of Optically-Active Vinyl Sulphoxides"
M. A. Brimble and B. R. Davis,
Tetrahedron, 1985, 41, 4965-4971.
Reviews - Refereed Journals and Book Chapters Publications - Refereed Database Entries and Book Reviews
1.
"Organic Synthesis Highlights II"
Edited by H. Waldmann. VCH: Weinheim, 1995, 407pp, hardback. DM 148. ISBN 3-527029200-4. Book review by M. A. Brimble
Synthesis, 1996, 305.
Reviews - Refereed Journals and Book Chapters Publications - Non-Refereed Journals
1.
"Strategic Synthesis: Science or Service"
M. A. Brimble and D. D. Rowan,
Chemistry in New Zealand, 1993, 57, 6-8.
2.
"Apple Scald: Unravelling the Chemistry"
M. A. Brimble, P. F. Reay, D. D. Rowan and J. A. Spicer,
Chemistry in New Zealand, 1994, 58, 29-30.
3.
"Synthesis of Biologically Active Natural Products"
M. A. Brimble,
Chemistry in New Zealand,1995, 58, 15-18.
4.
"The Synthesis of Potential Chemotherapeutic Agents Based on Leads from Nature"
M. A. Brimble,
Chemistry in Australia, 2001, 68, 15-17.
5.
"The Synthesis of Potential Chemotherapeutic Agents Based on Leads from Nature"
M. A. Brimble,
Federation of Asian Chemical Societies Journal, 2001, 24-28.
6.
"Synthetic Studies Towards Natural Products Containing Bis-spiroacetals"
M. A. Brimble,
Federation of Asian Chemical Societies Journal, 2002, 12-15.
7.
"Pushing Out Research Boundaries in Medicinal Chemistry"
M. A. Brimble,
New Zealand Pharmacy, 2002, 3, 15.
8.
"Turning Toxins into Medicines"
M. A. Brimble and M. S. Levi,
Chemistry in New Zealand, 2003, 66, 18-24.
9.
"Synthesis of Pharmaceuticals Using Molecular Chess and Automated Synthesis"
M. A. Brimble,
Chemistry in New Zealand, 2004, 68, 5-9.
10.
"Professor Jim Coxon. A Tribute"
M. A. Brimble and P. Steel,
Archive for Organic Chemistry, 2006, (iii), 1-5.
11.
"Chemistry Research: Making Molecules for Medicines"
M. A. Brimble,
p864-865 in Chemistry Textbook, J. W. Wiley and Sons Australia, Ltd.,
eds. A. Blackman, S. E. Bottle, S. Schmid, M. Mocerino and U. Wille, 2008, ISBN 9 78047081 0866 (pbk).
12.
"Equipment Access for Graduate Students – The First Hurdle" M. A. Brimble,
Royal Society of New Zealand Alert Editorial, Issue 479, 5th July, 2007.
13.
"Science of Synthesis – volume 28: Compounds with Two Carbon-Heteroatom Bonds: Quinones and Heteroatom Analogues" Volume editor A. G. Griesbeck. Georg Thieme Verlag:
Stuttgart, 2006, 1006 pp, hardback. ISBN 3-13-118791-3 (RoW); ISBN
1-58890-460-1 (US),
Book review by M. A. Brimble Synthesis, 2007, 18, 2924.
Reviews - Refereed Journals and Book Chapters Patents
1.
P. D. Gluckman, M. A. Brimble, D. Wilson, F. C. Tortella, A. J. Williams, X.-C. M. Lu, J. A. Hartings and D. Gryder,
"Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate"
U.S. Pat. Appl. Publ., 2006, 42pp., Cont.-in-part of U.S. Ser. No.
315,784. CODEN:
USXXCO US 2006251649 A1 20061109 CAN
145:483760 AN 2006:1173951.
2.
P. D. Gluckman, J. Guan, M. A. Woodnorth and M. A. Brimble,
"Cognitive enhancement and cognitive therapy using glycyl-L-2-methylprolyl-L-glutamic acid"
U.S. Pat. Appl. Publ., 2007, 42pp., Cont.-in-part of U.S. Ser. No.
314,424. CODEN:
USXXCO US 2007004641 A1 20070104 CAN
146:101046 AN 2007:17782.
3.
M. A. Brimble and J. Guan,
"Cyclic G-2-allylproline in treatment of Parkinson's disease"
U.S. Pat. Appl. Publ., 2006, 35 pp., Cont.-in-part of U.S. Ser.
No. 570,395. CODEN:
USXXCO US 2006258663 A1 20061116 CAN
145:500129 AN 2006:1204622.
4.
F. Sieg, M. A. Brimble and V. J. Muir,
"Neural regeneration peptides and methods for their use" PCT Int. Appl., 2006, 53pp. CODEN:
PIXXD2 WO 2006121926 A2 20061116 CAN
145:500131 AN 2006:1206263.
5.
P. W. R. Harris and M. A. Brimble,
"Preparation of neuroprotective macrocyclic compounds"
PCT Int. Appl., 2004, 106 pp. CODEN:
PIXXD2 WO 2004084809 A2 20041007 CAN
141:314630 AN 2004:817638.
6.
"Analogues of Peramine"
M. A. Brimble and D. D. Rowan,
NZ Patent No. 221195,
Filing date 24/07/87.
7.
P. D. Gluckman, G. B. Thomas, J. Guan, M. Dragunow, A. K. Anand, N. K. De Rosbo, F. Sieg and M. A. Brimble,
"Effects of glycyl-2 methyl prolyl glutamate on neurodegeneration" U.S.
Pat. Appl. Publ., 2007, 48pp., Cont.-in-part of U.S. Ser. No.
155,864. CODEN:
USXXCO US 2007298009 A1 20071227 CAN
148:70180 AN 2007:1475586.
8.
P. W. R. Harris, M. A. Brimble and F. Sieg,
"Synthetic analogues of neural regeneration peptides"
PCT Int. Appl., 2009, 42pp. CODEN:
PIXXD2 WO 2009051844 A1 20090423 CAN
150:439069 AN 2009:490629.
9.
"Process for Purifying a Compound" P. W. R. Harris and M. A. Brimble, NZ Patent Provisional Appl.;
Filing Date: 09/10/07.
10.
N. A. Abood and M. A.Brimble,
"GPE analogs and peptidomimetics"
PCT Int. Appl., 2002, 40 pp. CODEN:
PIXXD2 WO 2002094856 A2 20021128 CAN
137:380041 AN 2002:906272.
11.
12.
M. A. Brimble, J. Guan and F. Sieg,
"Preparation of neuroprotective bicyclic compounds"
PCT Int. Appl., 2005, 64 pp. CODEN:
PIXXD2 WO 2005023815 A2 20050317 CAN
142:316864 AN 2005:238992.
13.
M. A. Brimble, P. W. R. Harris and F. Sieg,
"Preparation of analogs of glycyl-prolyl-glutamate as neuroprotective agents"
PCT Int. Appl., 2006, 101 pp. CODEN:
PIXXD2 WO 2006127702 A2 20061130 CAN 146:28049
AN 2006:1252883.
14.
M. A. Brimble, P. W. R. Harris and F. Sieg,
"Preparation of analogs of glycyl-prolyl-glutamate as neuroprotective agents"
U.S. Pat. Appl. Publ., 2008, 48pp., Cont.-in-part of Appl. No.
PCT/US2006/019909. CODEN:
USXXCO US 2008145335 A1 20080619 CAN
149:79898 AN 2008:743334.
Reviews - Refereed Journals and Book Chapters 2006
1.
"Instant Insight: Life at the Extremes"
Z. E. Wilson and M. A. Brimble,
Chemistry World, 2008, 5, B95.
2.
"Synthetic Studies Towards Shellfish Toxins Containing Spiroacetal Units"
M. A. Brimble, R. Halim
Pure and Applied Chemistry, 2007, 79,153-162.
3.
"Synthetic Studies Towards the Pectenotoxins: A Review"
M. A. Brimble and R. Halim,
Organic and Biomolecular Chemistry, 2006, 4, 4048-4058. (Invited Review)
4.
"A Review of Agents Patented for their Neuroprotective Properties"
M. A. Brimble and M. S. Levi,
Recent Patents in CNS Drug Discovery, 2006, 1, 139-146.
5.
"Pyrans and Benzo Derivatives: Synthesis"
M. A. Brimble, J. Sperry and J. S. Gibson,
Comprehensive Heterocyclic Chemistry III,
eds. A. R. Katritzky, C. A. Ramsden, E. F. V. Scriven and R. J. K. Taylor, Elsevier, Oxford, 2008, 7, 419-700.
6.
"Polyether Antibiotics"
M. A. Brimble,
Kirk-Othmer Encyclopedia of Chemical Technology, 5th Edition,
ed. A. Seidel, John Wiley & Sons, Inc., 2006, 20, 119-148.
7.
"Pyranonaphthoquinones–Isolation, Biological Activity and Synthesis" J. Sperry, P. Bachu and M. A. Brimble,
Natural Product Reports, 2008, 25, 376-400. (Invited Review - selected for inclusion in Chemical Biology, 2008, issue 5)
8.
"2-Trimethylsilyloxyfuran, CAS No: 61550-02- Update" J. Sperry and M. A. Brimble, Electronic Encyclopedia of Reagents for Organic Synthesis [e-EROS],
eds. L. A. Paquette, D. Crich, P. L. Fuchs and P. Wipf, John Wiley & Sons Inc., 2007.
9.
"Use of Stabilized Phthalide Anion Annulation Reactions in Synthesis: An Update" K. Rathwell and M. A. Brimble,
Synthesis, 2007, 643-66.
(Invited Review)
10.
"Synthesis of Macrocyclic Shellfish Toxins Containing Spiroimine Moieties" P. D. O'Connor and M. A. Brimble,
Natural Product Reports, 2007, 24, 869-88.
(Invited Review)
11.
"Molecules from the Extremes of Life" Z. E. Wilson and M. A. Brimble,
Natural Product Reports, 2009, 26, 44-71. (Invited Review - selected for front cover and as an Instant Insight article in Chemical Biology, 2008, issue 9)
12.
"A Review of Neuroprotective Agents"
M. A. Brimble and M. S. Levi,
Frontiers in Medicinal Chemistry, ed. A. B. Reitz and A. U. Rahman, Bentham, Karachi, 2006, 3, 163-194.
13.
"Polyether Antibiotics" M. A. Brimble,
Kirk-Othmer Encyclopedia of Chemical Technology Online Edition,
ed. A. Seidel, John Wiley & Sons, Inc., 2003.
14.
"Pyranonaphthoquinone Antibiotics – Isolation, Structure and Biological Activity"
M. A. Brimble,L. J. Duncalf and M. R. Nairn,
Natural Product Reports, 1999, 16, 267-281.
15.
"Synthesis of Bis-spiroacetal Ring Systems"
M. A. Brimble and F. A. Fares,
Tetrahedron, 1999, 55, 7661-7706.
16.
"Synthetic Studies Towards Natural Products Containing Bis-spiroacetals"
M. A. Brimble,
Journal of Heterocyclic Chemistry, 1999, 36, 1373-1389.
17.
"Synthetic Strategies Towards Pyranonaphthoquinone Antibiotics"
M. A. Brimble,
Pure and Applied Chemistry, 2000, 72, 1635-1639.
18.
"Synthetic Strategies Towards Pyranonaphthoquinone Antibiotics"
M. A. Brimble, M. R. Nairn and H. Prabaharan,
Tetrahedron, 2000, 56, 1937-1992.
19.
"Di-(–)-(1R,2S)-2-phenyl-1-cyclohexyl Diazenedicarboxylate" M. A. Brimble, Electronic Encyclopedia of Reagents for Organic Synthesis [e-EROS],
eds L. A. Paquette,D. Crich, P. L. Fuchs and P. Wipf, John Wiley and Sons Inc., 2001.
20.
"Chemistry of Bis-spiroacetal Systems: Natural Products, Synthesis and Stereochemistry"
M. A. Brimble and D. P. Furkert,
Current Organic Chemistry, 2003, 7, 1461-1484.
21.
"A Review of Neuroprotective Agents"
M. A. Brimble and M. S. Levi,
Current Medicinal Chemistry, 2004, 11, 2383-2398.
22.
"Alkylarsenic, -antimony, and -bismuth Compounds"
M. A. Brimble and M. S. Levi,
Comprehensive Organic Functional Group Transformations II, Chapter 2.09,ed. A. R. Katritzky and R. J. K. Taylor, Elsevier Ltd., Oxford, 2005, 2, 463-484.
23.
"A Review of Advances in the Synthesis of Analogues of the Delphinium Alkaloid Methyllycaconitine" K. J. Goodall, D. Barker and M. A. Brimble, Synlett, 2005, 1809-1827.
